Synthetic Matrices to Serve as Niches for Muscle Cell Transplantation
نویسندگان
چکیده
منابع مشابه
Parent stem cells can serve as niches for their own daughter cells
Stem cells integrate inputs from multiple sources. Stem cell niches provide signals that promote stem cell maintenance1-2, while differentiated daughter cells are known to provide feedback signals to regulate stem cell replication and differentiation3-6. Recently, stem cells have been shown to regulate themselves using an autocrine mechanism7. The existence of a “stem cell niche” was first post...
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Thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. For β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. Stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...
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Aims This study sought to extend the inclusion criteria for hepatocellular carcinoma (HCC) liver transplantation (LT), particularly addressing the safety and effectiveness of pre-LT transarterial chemoembolization (TACE). Materials and Methods Our study included 115 patients with HCC who underwent LT after TACE. The response measured after each TACE session was based on the mRECIST criteria: ...
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Stem cells are required to support the indeterminate growth style of plants. Meristems are a plants stem cell niches that foster stem cell survival and the production of descendants destined for differentiation. In shoot meristems, stem cell fate is decided at the populational level. The size of the stem cell domain at the meristem tip depends on signals that are exchanged with cells of the org...
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Stem cells are characterized by their dual ability to reproduce themselves (self-renew) and specialize (differentiate), yielding a plethora of daughter cells that maintain and regenerate tissues. In contrast to their embryonic counterparts, adult stem cells retain their unique functions only if they are in intimate contact with an instructive microenvironment, termed stem cell niche. In these n...
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ژورنال
عنوان ژورنال: Cells Tissues Organs
سال: 2012
ISSN: 1422-6421,1422-6405
DOI: 10.1159/000331414